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New Results of Cancer Translational Research

Cancer research combines relevance comes from the laboratory and the clinic to get new business analysis, treatment and prevention strategies against cancer. Apoptosis, the cell is designed to die that way applied research as a new way of treatment plans for cancer. The idea is to induce cancer cells to kill themselves. This new treatment approach is a novel serving therapies have numerous disadvantages. But this new finding also shows the number of complications.
Apoptosis as a typical stress response

All cells are going to die. They are programmed to do this. This was proven to be a physiological mechanism to maintain the homeostasis. When a toxic substance enters the cell, the opportunity would be suicide to store material to prevent it from causing further damage to other cells and tissues. Chemotherapy drugs that can be used to treat cancer work toxins to cancer cells. Thus, there is debate about how possible can make cancer cells to kill themselves by apoptosis or simply kill cancer cells through the cytotoxic drugs.

Cell toxicity or cell death

Most chemotherapy drugs inhibit cancer by blocking the DNA, mRNA or protein production, causing a direct problem for the DNA, blocking DNA replication enzymes or inducing chromosome segregation. Cancer given these drugs can get damages against the mitotic mechanism and cell membrane permeability or become senescent or old. It has been reported in cancer cells that have intact apoptotic system, to follow the programmed cell death mechanism of, in response to toxins in the drugs. It's really moist chemotherapy whether cells die due to lethal effect of the toxin or toxins that have enabled suicidal system of cells.

Helpful remarks on apoptosis

If chemotherapy agents working under either cell toxicity or cell death, is an apoptosis research has thus far useless? Not too far. The new results of apoptosis are certainly not all futile, it was found that treatments that includes chemotherapy addition to apoptosis inducers can be much better. Acting alone, they could struggle to get rid of the offspring of cancer cells that have been proof against either treatment. Remedy that is inherently toxic and blocks an important metabolic pathway may be more powerful. In addition, new data on apoptosis using to look at the existing treatment of employees with cancer. A lot of the issues that have not yet been found in cancer research as important to look for safer and more effective treatment.